{"product_id":"snap-8","title":"SNAP-8","description":"\u003ch1 data-path-to-node=\"2\"\u003eAcetyl Octapeptide-3 (SNAP-8)\u003c\/h1\u003e\n\u003cp data-path-to-node=\"3\"\u003e\u003cb data-path-to-node=\"3\" data-index-in-node=\"0\"\u003eHigh-Purity Laboratory Research Reagent\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"3\"\u003e\u003ci data-path-to-node=\"3\" data-index-in-node=\"40\"\u003eFOR LABORATORY USE ONLY. Not intended for therapeutic, diagnostic, or human\/animal application.\u003c\/i\u003e\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"4\"\u003eProduct Overview\u003c\/h2\u003e\n\u003cp data-path-to-node=\"5\"\u003eAcetyl Octapeptide-3 (SNAP-8) is a premium, high-purity synthetic octapeptide reference compound structurally derived from the N-terminal region of SNAP-25. It is engineered specifically for institutional, laboratory-based biochemical and dermatological research. In contemporary in-vitro studies, it is primarily utilized to investigate SNARE-complex interaction pathways, vesicle-fusion signaling modulation, and surface-appearance benchmarking.\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"6\"\u003eTechnical Specifications\u003c\/h2\u003e\n\u003ctable data-path-to-node=\"7\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eParameter\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eSpecification\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,1,0,0\"\u003e\u003cb data-path-to-node=\"7,1,0,0\" data-index-in-node=\"0\"\u003eProduct Ref\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,1,1,0\"\u003eAcetyl Octapeptide-3 (Research Reagent)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,2,0,0\"\u003e\u003cb data-path-to-node=\"7,2,0,0\" data-index-in-node=\"0\"\u003eIUPAC \/ INCI Name\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,2,1,0\"\u003eAcetyl Octapeptide-3\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,3,0,0\"\u003e\u003cb data-path-to-node=\"7,3,0,0\" data-index-in-node=\"0\"\u003eChemical Class\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,3,1,0\"\u003eSynthetic peptide \/ Signal-modulating octapeptide\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,4,0,0\"\u003e\u003cb data-path-to-node=\"7,4,0,0\" data-index-in-node=\"0\"\u003eChemical Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,4,1,0\"\u003eAc-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,5,0,0\"\u003e\u003cb data-path-to-node=\"7,5,0,0\" data-index-in-node=\"0\"\u003eCAS Number\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,5,1,0\"\u003e868844-74-0\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,6,0,0\"\u003e\u003cb data-path-to-node=\"7,6,0,0\" data-index-in-node=\"0\"\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,6,1,0\"\u003e~889 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,7,0,0\"\u003e\u003cb data-path-to-node=\"7,7,0,0\" data-index-in-node=\"0\"\u003eAmino Acid Count\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,7,1,0\"\u003e8 amino acids (Octapeptide)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,8,0,0\"\u003e\u003cb data-path-to-node=\"7,8,0,0\" data-index-in-node=\"0\"\u003ePurity Standard\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,8,1,0\"\u003e≥99% (HPLC verified; MS identity confirmed; COA available)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,9,0,0\"\u003e\u003cb data-path-to-node=\"7,9,0,0\" data-index-in-node=\"0\"\u003eStorage (Lyophilized)\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,9,1,0\"\u003e2–8°C in sealed research unit\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,10,0,0\"\u003e\u003cb data-path-to-node=\"7,10,0,0\" data-index-in-node=\"0\"\u003eStorage (Reconstituted)\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,10,1,0\"\u003e−20°C (single-use aliquots recommended per lab protocol)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,11,0,0\"\u003e\u003cb data-path-to-node=\"7,11,0,0\" data-index-in-node=\"0\"\u003eShelf Life\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"7,11,1,0\"\u003e24 months from manufacture date (lyophilized, sealed, −20°C)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2 data-path-to-node=\"8\"\u003eResearch Applications \u0026amp; Mechanisms\u003c\/h2\u003e\n\u003cp data-path-to-node=\"9\"\u003eIn highly controlled, cell-free laboratory environments, this octapeptide is utilized across several biochemical study areas:\u003c\/p\u003e\n\u003cul data-path-to-node=\"10\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,0,0\"\u003e\u003cb data-path-to-node=\"10,0,0\" data-index-in-node=\"0\"\u003eSNARE Complex Interaction Assays:\u003c\/b\u003e Investigating competitive binding with SNAP-25 fragments within the SNARE complex using established biochemical assays.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,1,0\"\u003e\u003cb data-path-to-node=\"10,1,0\" data-index-in-node=\"0\"\u003eVesicle-Fusion Signaling:\u003c\/b\u003e Measuring the partial modulation of vesicle-fusion signaling pathways at defined laboratory concentrations.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,2,0\"\u003e\u003cb data-path-to-node=\"10,2,0\" data-index-in-node=\"0\"\u003eDelivery Efficiency Engineering:\u003c\/b\u003e Evaluating stratum corneum permeation efficiency using advanced delivery models, such as dissolving microneedle (DMN) technology.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,3,0\"\u003e\u003cb data-path-to-node=\"10,3,0\" data-index-in-node=\"0\"\u003eDual-Pathway Assays:\u003c\/b\u003e Investigating combined, multi-pathway signaling interactions alongside complementary peptide reference compounds, such as Pentapeptide-18.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"11\"\u003eComparative Research Context (Table 1)\u003c\/h2\u003e\n\u003ctable data-path-to-node=\"12\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePeptide\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eOrigin \u0026amp; Structure\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eLaboratory Target\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003ePrimary Research Focus\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003ePubMed Ref\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,1,0,0\"\u003e\u003cb data-path-to-node=\"12,1,0,0\" data-index-in-node=\"0\"\u003eSNAP-8\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,1,1,0\"\u003eSynthetic octapeptide\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,1,2,0\"\u003eSNARE-complex assays\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,1,3,0\"\u003eSurface-appearance benchmarking\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,1,4,0\"\u003ePMID: 33246344\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,2,0,0\"\u003e\u003cb data-path-to-node=\"12,2,0,0\" data-index-in-node=\"0\"\u003eP21 (P021)\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,2,1,0\"\u003eSmall-molecule mimetic\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,2,2,0\"\u003eBDNF-pathway modulation\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,2,3,0\"\u003eCellular neurogenesis models\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,2,4,0\"\u003ePMID: 20600002\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,3,0,0\"\u003e\u003cb data-path-to-node=\"12,3,0,0\" data-index-in-node=\"0\"\u003ePinealon\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,3,1,0\"\u003eSynthetic tripeptide\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,3,2,0\"\u003eMAPK\/ERK pathway\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,3,3,0\"\u003eCellular gene-expression models\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"12,3,4,0\"\u003ePMID: 21978084\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2 data-path-to-node=\"13\"\u003eWhy Source From Profound Aminos?\u003c\/h2\u003e\n\u003cul data-path-to-node=\"14\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-path-to-node=\"14,0,0\" data-index-in-node=\"0\"\u003eIndependent Identity Verification:\u003c\/b\u003e Our reagent documentation is supported by laboratory-verified analytical benchmarks. Assays demonstrate that Acetyl Octapeptide-3 exhibits enhanced molecular stability compared to Acetyl Hexapeptide-8 at equivalent concentrations.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-path-to-node=\"14,1,0\" data-index-in-node=\"0\"\u003eDelivery Engineering Data:\u003c\/b\u003e We provide comprehensive data summaries on device-enabled delivery systems. Published research suggests that Dissolving Microneedle (DMN) platforms can improve stratum corneum permeation efficiency up to 40-fold versus passive topical application.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,2,0\"\u003e\u003cb data-path-to-node=\"14,2,0\" data-index-in-node=\"0\"\u003eRegulatory \u0026amp; COA Transparency:\u003c\/b\u003e We maintain strict compliance with federal research reagent standards (post-MoCRA). Every batch is accompanied by a Certificate of Analysis (COA) confirming purity and chemical identity via HPLC and Mass Spectrometry.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"15\"\u003eRegulatory \u0026amp; Safety Compliance\u003c\/h2\u003e\n\u003cp data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eRESEARCH USE ONLY (RUO).\u003c\/b\u003e This compound is supplied strictly for in-vitro biochemical testing, cellular assays, and laboratory calibration.\u003c\/p\u003e\n\u003cul data-path-to-node=\"17\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,0,0\"\u003e\u003cb data-path-to-node=\"17,0,0\" data-index-in-node=\"0\"\u003eStrict Prohibition:\u003c\/b\u003e Any intent to use this product for internal or external human or animal application is a strict violation of federal regulations and our Terms of Service. Purchase constitutes an acknowledgment of its RUO-only status.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,1,0\"\u003e\u003cb data-path-to-node=\"17,1,0\" data-index-in-node=\"0\"\u003eMarketing Restrictions:\u003c\/b\u003e No claims regarding physiological, therapeutic, cosmetic, or diagnostic outcomes are made or implied.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,2,0\"\u003e\u003cb data-path-to-node=\"17,2,0\" data-index-in-node=\"0\"\u003eLaboratory Handling Protocol:\u003c\/b\u003e Researchers must adhere to institutional biosafety protocols and wear appropriate PPE (chemical-resistant gloves, eye protection) during reconstitution and handling. Always consult the Safety Data Sheet (SDS) for CAS 868844-74-0 prior to use.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"19\"\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eIs this product intended for human use, personal wellness, or self-administration?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"20\"\u003eNo. Acetyl Octapeptide-3 is exclusively a Research Use Only (RUO) laboratory reagent for qualified institutional researchers.\u003c\/p\u003e\n\u003cp data-path-to-node=\"21\"\u003e\u003cb data-path-to-node=\"21\" data-index-in-node=\"0\"\u003eDoes this compound have FDA approval?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"21\"\u003eNo. It is not approved for any therapeutic, cosmetic, dietary, or diagnostic indication.\u003c\/p\u003e\n\u003cp data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003eHow does SNAP-8 differ from Acetyl Hexapeptide-8 in laboratory settings?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"22\"\u003eIt is a structurally extended iteration (eight amino acids instead of six) that is actively studied for potential differences in molecular stability and SNARE complex binding behaviors.\u003c\/p\u003e\n\u003cp data-path-to-node=\"23\"\u003e\u003cb data-path-to-node=\"23\" data-index-in-node=\"0\"\u003eWhat is the primary challenge in topical peptide research?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"23\"\u003eThe stratum corneum layer heavily restricts the passive permeation of large hydrophilic peptides, driving research into advanced delivery models like DMNs.\u003c\/p\u003e\n\u003cp data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eWhat concentrations should be utilized?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"24\"\u003eResearchers must consult the specific methodology sections of cited peer-reviewed literature for precise laboratory parameters, assay system requirements, and standardized concentrations.\u003c\/p\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003eDoes the literature indicate complete pathway inhibition?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"25\"\u003eNo. Published in-vitro data indicates partial modulation of vesicle-fusion signaling pathways, not complete inhibition.\u003c\/p\u003e","brand":"BioLink Analytica","offers":[{"title":"Default Title","offer_id":45052805873733,"sku":null,"price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0729\/0060\/8069\/files\/SNAP-8_-_10_MG.png?v=1782365654","url":"https:\/\/www.biolinkanalytica.com\/products\/snap-8","provider":"BioLink Analytica","version":"1.0","type":"link"}