{"title":"Other example products","description":null,"products":[{"product_id":"other-example-product-1","title":"NAD+","description":"\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"markdown markdown-main-panel tutor-markdown-rendering enable-updated-hr-color\" id=\"model-response-message-contentr_48c623880b4668ce\" aria-live=\"polite\" aria-busy=\"false\" dir=\"ltr\"\u003e\n\u003ch3 data-path-to-node=\"0\"\u003eThe Anatomy of the \u003cspan class=\"math-inline\" data-math=\"\\text{NAD}^+\" data-index-in-node=\"19\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eNAD\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e Molecule\u003c\/h3\u003e\n\u003cp data-path-to-node=\"1\"\u003eNicotinamide adenine dinucleotide (\u003cspan class=\"math-inline\" data-math=\"\\text{NAD}^+\" data-index-in-node=\"35\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eNAD\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e) is a dinucleotide, meaning it is constructed from two primary nucleotide building blocks joined together to form a larger complex.\u003c\/p\u003e\n\u003cdiv class=\"attachment-container search-images\"\u003e\n\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003cdiv class=\"image-container spark-licensed-center hide-from-message-actions ng-star-inserted\" data-full-size-image-uri=\"https:\/\/encrypted-tbn1.gstatic.com\/licensed-image?q=tbn:ANd9GcQrjyzFoj2_Fs_O97zQisnLLhMgWBFjxdlQnVxzE3tJ2REPyOX_k9Qwgi2fU8Tv3ABZMu60t47E-zppjvdyw4VDqYER8ZFkrxjmF36dbcwtOaPZnW8\"\u003e\n\u003cdiv class=\"overlay-container hero-overlay-container ng-star-inserted\"\u003e\n\u003c!----\u003e\u003cbutton class=\"image-button ng-star-inserted\"\u003e\u003cimg loading=\"lazy\" class=\"spark-licensed-square hero-image loaded\" alt=\"Nicotinamide adenine dinucleotide chemical structure, AI generated\" width=\"2048\" height=\"2048\" src=\"https:\/\/encrypted-tbn1.gstatic.com\/licensed-image?q=tbn:ANd9GcQrjyzFoj2_Fs_O97zQisnLLhMgWBFjxdlQnVxzE3tJ2REPyOX_k9Qwgi2fU8Tv3ABZMu60t47E-zppjvdyw4VDqYER8ZFkrxjmF36dbcwtOaPZnW8\"\u003e\u003c\/button\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4 data-path-to-node=\"3\"\u003eCore Structural Components\u003c\/h4\u003e\n\u003cul data-path-to-node=\"4\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,0,0\"\u003e\u003cb data-path-to-node=\"4,0,0\" data-index-in-node=\"0\"\u003eThe Nicotinamide Ring:\u003c\/b\u003e This is the active, electron-carrying portion of the molecule. It features a six-membered ring containing a positively charged nitrogen atom (\u003cspan class=\"math-inline\" data-math=\"\\text{N}^+\" data-index-in-node=\"165\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eN\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e), which gives the molecule its \u003cspan class=\"math-inline\" data-math=\"\\text{NAD}^+\" data-index-in-node=\"207\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eNAD\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e designation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,1,0\"\u003e\u003cb data-path-to-node=\"4,1,0\" data-index-in-node=\"0\"\u003eThe Adenine Ring:\u003c\/b\u003e A double-ring purine base (adenine) identical to the one found in DNA and ATP. It serves as a structural anchor that cellular enzymes recognize and bind to.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,2,0\"\u003e\u003cb data-path-to-node=\"4,2,0\" data-index-in-node=\"0\"\u003eTwo Ribose Sugars:\u003c\/b\u003e Each of the two bases (nicotinamide and adenine) is attached to its own five-carbon ribose sugar ring.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,3,0\"\u003e\u003cb data-path-to-node=\"4,3,0\" data-index-in-node=\"0\"\u003eThe Pyrophosphate Bridge:\u003c\/b\u003e The two halves of the molecule are securely connected by a central bridge consisting of two phosphate groups.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"6\"\u003eRelationship to Precursors (NMN and NR)\u003c\/h3\u003e\n\u003cp data-path-to-node=\"7\"\u003eBoosting compounds like \u003cb data-path-to-node=\"7\" data-index-in-node=\"24\"\u003eNMN\u003c\/b\u003e (Nicotinamide Mononucleotide) and \u003cb data-path-to-node=\"7\" data-index-in-node=\"62\"\u003eNR\u003c\/b\u003e (Nicotinamide Riboside) are the direct structural precursors, or \"building blocks,\" of the full \u003cspan class=\"math-inline\" data-math=\"\\text{NAD}^+\" data-index-in-node=\"161\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eNAD\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e molecule:\u003c\/p\u003e\n\u003cul data-path-to-node=\"8\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,0,0\"\u003e\u003cb data-path-to-node=\"8,0,0\" data-index-in-node=\"0\"\u003eNicotinamide Riboside (NR):\u003c\/b\u003e If you isolate the nicotinamide ring and its attached ribose sugar—removing the phosphate groups and the entire adenine half of the molecule—you are left with NR.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,1,0\"\u003e\u003cb data-path-to-node=\"8,1,0\" data-index-in-node=\"0\"\u003eNicotinamide Mononucleotide (NMN):\u003c\/b\u003e If you take NR and attach exactly \u003ci data-path-to-node=\"8,1,0\" data-index-in-node=\"69\"\u003eone\u003c\/i\u003e phosphate group to it, you get NMN. Structurally, NMN is precisely one-half of the complete \u003cspan class=\"math-inline\" data-math=\"\\text{NAD}^+\" data-index-in-node=\"165\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eNAD\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e dinucleotide.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cblockquote data-path-to-node=\"9\"\u003e\n\u003cp data-path-to-node=\"9,0\"\u003e\u003cb data-path-to-node=\"9,0\" data-index-in-node=\"0\"\u003eCellular Assembly:\u003c\/b\u003e In a cellular environment (or a laboratory bioassay), enzymes take these smaller, highly bioavailable precursor blocks (NMN or NR) and synthesize them into the complete, dual-nucleotide \u003cspan class=\"math-inline\" data-math=\"\\text{NAD}^+\" data-index-in-node=\"205\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eNAD\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e structure. Once fully assembled, the molecule is able to facilitate critical biological processes, including energy metabolism, redox signaling, and sirtuin-dependent regulation.\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003c\/div\u003e\n\u003c!----\u003e\n\u003c\/div\u003e","brand":"BioLink Analytica","offers":[{"title":"NAD+500","offer_id":44913876074565,"sku":"NJ500","price":99.0,"currency_code":"USD","in_stock":true},{"title":"NAD+1000","offer_id":44913876107333,"sku":"NJ1000","price":189.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0729\/0060\/8069\/files\/NAD_-_NJ500.png?v=1782365653"},{"product_id":"other-example-product-2","title":"TIRZEPATIDE","description":"\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"markdown markdown-main-panel tutor-markdown-rendering enable-updated-hr-color\" id=\"model-response-message-contentr_e5823fe3018a1002\" aria-live=\"polite\" aria-busy=\"false\" dir=\"ltr\"\u003e\n\u003cp data-path-to-node=\"0\"\u003eThis 75-Format High-Mass Research Reagent empowers researchers to reconstitute a single, consistent master batch of lyophilized dual-agonist ligand (Tirzepatide) optimized for laboratory stock solutions. By enabling the creation of a unified master batch, it guarantees baseline uniformity for longitudinal metabolic \u003ci data-path-to-node=\"0\" data-index-in-node=\"317\"\u003ein-vitro\u003c\/i\u003e studies and thoroughly eliminates the inter-batch variance commonly associated with smaller aliquots.\u003c\/p\u003e\n\u003cp data-path-to-node=\"1\"\u003e\u003cb data-path-to-node=\"1\" data-index-in-node=\"0\"\u003eStrictly for research purposes only. Not for human use.\u003c\/b\u003e\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"3\"\u003eTirz 75 (High-Mass) | Dual-Agonist Ligand | CAS 2023788-19-2 | Profound Aminos\u003c\/h2\u003e\n\u003ch3 data-path-to-node=\"4\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cdiv class=\"horizontal-scroll-wrapper\"\u003e\n\u003cdiv class=\"table-block-component\"\u003e\n\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003cdiv class=\"table-block has-export-button new-table-style is-at-scroll-start is-at-scroll-end\"\u003e\n\u003cdiv class=\"table-content\" data-hveid=\"0\" data-ved=\"0CAAQ3ecQahgKEwi8h9bVldKUAxUAAAAAHQAAAAAQ2Vs\"\u003e\n\u003ctable data-path-to-node=\"5\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan data-path-to-node=\"5,0,0,0\"\u003eSpecification\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan data-path-to-node=\"5,0,1,0\"\u003eDetail\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,1,0,0\"\u003e\u003cb data-path-to-node=\"5,1,0,0\" data-index-in-node=\"0\"\u003eProduct Ref\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,1,1,0\"\u003eTirz 75 (High-Mass Reagent)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,2,0,0\"\u003e\u003cb data-path-to-node=\"5,2,0,0\" data-index-in-node=\"0\"\u003eChemical Class\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,2,1,0\"\u003eDual-Agonist Peptide Ligand\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,3,0,0\"\u003e\u003cb data-path-to-node=\"5,3,0,0\" data-index-in-node=\"0\"\u003eCAS Number\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,3,1,0\"\u003e2023788-19-2\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,4,0,0\"\u003e\u003cb data-path-to-node=\"5,4,0,0\" data-index-in-node=\"0\"\u003eMolecular Formula\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,4,1,0\"\u003e\u003cspan class=\"math-inline\" data-math=\"\\text{C}_{225}\\text{H}_{348}\\text{N}_{48}\\text{O}_{68}\" data-index-in-node=\"0\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eC\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t vlist-t2\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mord mtight\"\u003e225\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-s\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eH\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t vlist-t2\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mord mtight\"\u003e348\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-s\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eN\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t vlist-t2\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mord mtight\"\u003e48\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-s\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003eO\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t vlist-t2\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mord mtight\"\u003e68\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-s\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,5,0,0\"\u003e\u003cb data-path-to-node=\"5,5,0,0\" data-index-in-node=\"0\"\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,5,1,0\"\u003e~4813.53 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,6,0,0\"\u003e\u003cb data-path-to-node=\"5,6,0,0\" data-index-in-node=\"0\"\u003eSequence Length\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,6,1,0\"\u003e39 Amino Acids\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,7,0,0\"\u003e\u003cb data-path-to-node=\"5,7,0,0\" data-index-in-node=\"0\"\u003eFormat\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,7,1,0\"\u003eLyophilized Filtered Cake\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,8,0,0\"\u003e\u003cb data-path-to-node=\"5,8,0,0\" data-index-in-node=\"0\"\u003eMass Format\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,8,1,0\"\u003eHigh-Mass Unit (75)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,9,0,0\"\u003e\u003cb data-path-to-node=\"5,9,0,0\" data-index-in-node=\"0\"\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,9,1,0\"\u003e≥99% (RP-HPLC Verified)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,10,0,0\"\u003e\u003cb data-path-to-node=\"5,10,0,0\" data-index-in-node=\"0\"\u003eSolubility\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,10,1,0\"\u003eSoluble in BAC Water \/ Sterile Buffer\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,11,0,0\"\u003e\u003cb data-path-to-node=\"5,11,0,0\" data-index-in-node=\"0\"\u003eStorage\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,11,1,0\"\u003e-20°C (Desiccated)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,12,0,0\"\u003e\u003cb data-path-to-node=\"5,12,0,0\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"5,12,1,0\"\u003e\u003cb data-path-to-node=\"5,12,1,0\" data-index-in-node=\"0\"\u003eFor Research Use Only (RUO). Not for human use.\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"table-footer hide-from-message-actions\"\u003e\n\u003c!----\u003e\u003cbutton class=\"mdc-icon-button mat-mdc-icon-button mat-mdc-button-base mat-badge mat-unthemed mat-badge-overlap mat-badge-above mat-badge-after mat-badge-small mat-badge-hidden ng-star-inserted\" aria-label=\"More options\"\u003e\u003cspan class=\"mat-mdc-button-persistent-ripple mdc-icon-button__ripple\"\u003e\u003c\/span\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003cspan class=\"mat-focus-indicator\"\u003e\u003c\/span\u003e\u003cspan class=\"mat-mdc-button-touch-target\"\u003e\u003c\/span\u003e\u003c\/button\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 data-path-to-node=\"7\"\u003eProduct Overview\u003c\/h2\u003e\n\u003cp data-path-to-node=\"8\"\u003eThis product comprises a High-Mass Unit (75 Format) of the synthetic peptide ligand known as Tirz. It is a linear 39-amino acid chain that functions as a Dual-Agonist, targeting two distinct incretin receptor pathways simultaneously.\u003c\/p\u003e\n\u003cp data-path-to-node=\"9\"\u003eUnlike standard low-mass units often limited to single-assay use, this High-Mass Format is engineered specifically for high-throughput laboratories. It allows researchers to create a concentrated master stock solution, ensuring that every cellular culture or model in a longitudinal study receives an identical chemical concentration, thereby eliminating intra-experimental variability.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"10\"\u003eResearch Mechanism\u003c\/h3\u003e\n\u003cp data-path-to-node=\"11\"\u003eIn modern metabolic research, this ligand is utilized \u003ci data-path-to-node=\"11\" data-index-in-node=\"54\"\u003ein-vitro\u003c\/i\u003e to study:\u003c\/p\u003e\n\u003cul data-path-to-node=\"12\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,0,0\"\u003e\u003cb data-path-to-node=\"12,0,0\" data-index-in-node=\"0\"\u003eSynergistic Signaling:\u003c\/b\u003e How activating the GIP receptor alongside the GLP-1 receptor alters cellular energy homeostasis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,1,0\"\u003e\u003cb data-path-to-node=\"12,1,0\" data-index-in-node=\"0\"\u003eLipid Substrate Utilization:\u003c\/b\u003e Investigating how dual-pathway modulation influences adipocyte (fat cell) metabolism in controlled environments.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,2,0\"\u003e\u003cb data-path-to-node=\"12,2,0\" data-index-in-node=\"0\"\u003eReceptor Kinetics:\u003c\/b\u003e Measuring binding affinity without the interference of systemic insulinogenic feedback loops.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,3,0\"\u003e\u003cb data-path-to-node=\"12,3,0\" data-index-in-node=\"0\"\u003eSynergistic Mechanism of Action:\u003c\/b\u003e Distinct from mono-target ligands, Tirz exhibits simultaneous affinity for both GIP and GLP-1 recognition sites. This dual-receptor occupancy modulates intracellular cAMP flux, facilitating the investigation of synergistic signaling pathways in isolated cell cultures.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cblockquote data-path-to-node=\"13\"\u003e\n\u003cp data-path-to-node=\"13,0\"\u003e\u003cb data-path-to-node=\"13,0\" data-index-in-node=\"0\"\u003eChemical Diagram of Tirz 75\u003c\/b\u003e \u003ci data-path-to-node=\"13,0\" data-index-in-node=\"28\"\u003e(Placeholder for structural diagram)\u003c\/i\u003e Tirz 75 High-Mass Lyophilized Reagent Vial for Stock Solution – GIP\/GLP-1 Receptor Affinity Ligand – CAS 2023788-19-2\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003ch2 data-path-to-node=\"15\"\u003eComparative Research Context: Receptor Ligand Landscape\u003c\/h2\u003e\n\u003cdiv class=\"horizontal-scroll-wrapper\"\u003e\n\u003cdiv class=\"table-block-component\"\u003e\n\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003cdiv class=\"table-block has-export-button new-table-style has-scrollbar is-at-scroll-start\"\u003e\n\u003cdiv class=\"table-content\" data-hveid=\"0\" data-ved=\"0CAAQ3ecQahgKEwi8h9bVldKUAxUAAAAAHQAAAAAQ21s\"\u003e\n\u003ctable data-path-to-node=\"16\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan data-path-to-node=\"16,0,0,0\"\u003eFeature\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan data-path-to-node=\"16,0,1,0\"\u003eTirz (Dual-A)\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan data-path-to-node=\"16,0,2,0\"\u003eSema (Single-A)\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan data-path-to-node=\"16,0,3,0\"\u003eReta (Triple-A)\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,1,0,0\"\u003e\u003cb data-path-to-node=\"16,1,0,0\" data-index-in-node=\"0\"\u003eTarget Receptors\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,1,1,0\"\u003eGIP + GLP-1\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,1,2,0\"\u003eGLP-1 Only\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,1,3,0\"\u003eGIP + GLP-1 + Glucagon\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,2,0,0\"\u003e\u003cb data-path-to-node=\"16,2,0,0\" data-index-in-node=\"0\"\u003ePrimary Action\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,2,1,0\"\u003eSynergistic Modulation\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,2,2,0\"\u003eAgonist Signaling\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,2,3,0\"\u003eMulti-Pathway Flux\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,3,0,0\"\u003e\u003cb data-path-to-node=\"16,3,0,0\" data-index-in-node=\"0\"\u003eResearch Focus\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,3,1,0\"\u003eEnergy Homeostasis\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,3,2,0\"\u003eGlycemic Indices\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,3,3,0\"\u003eBasal Metabolic Rate\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,4,0,0\"\u003e\u003cb data-path-to-node=\"16,4,0,0\" data-index-in-node=\"0\"\u003eAssay Type\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,4,1,0\"\u003eDual-Receptor Binding\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,4,2,0\"\u003eSingle-Receptor Binding\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"16,4,3,0\"\u003eTriple-Receptor Binding\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"table-footer hide-from-message-actions\"\u003e\n\u003c!----\u003e\u003cbutton class=\"mdc-icon-button mat-mdc-icon-button mat-mdc-button-base mat-badge mat-unthemed mat-badge-overlap mat-badge-above mat-badge-after mat-badge-small mat-badge-hidden ng-star-inserted\" aria-label=\"More options\"\u003e\u003cspan class=\"mat-mdc-button-persistent-ripple mdc-icon-button__ripple\"\u003e\u003c\/span\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003cspan class=\"mat-focus-indicator\"\u003e\u003c\/span\u003e\u003cspan class=\"mat-mdc-button-touch-target\"\u003e\u003c\/span\u003e\u003c\/button\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 data-path-to-node=\"18\"\u003eWhy Source From Profound Aminos\u003c\/h2\u003e\n\u003col start=\"1\" data-path-to-node=\"19\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"19,0,0\"\u003e\u003cb data-path-to-node=\"19,0,0\" data-index-in-node=\"0\"\u003eThe \"Single-Stock\" Advantage\u003c\/b\u003e Experimental error often occurs when researchers pool multiple small units together. Our Tirz 75 Format empowers you to reconstitute one large volume of reagent. This ensures absolute homogeneity across your entire experiment, significantly improving data reproducibility and \u003cspan class=\"math-inline\" data-math=\"R^2\" data-index-in-node=\"305\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"strut\"\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord mathnormal\"\u003eR\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"pstrut\"\u003e\u003c\/span\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mord mtight\"\u003e2\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e values.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"19,1,0\"\u003e\u003cb data-path-to-node=\"19,1,0\" data-index-in-node=\"0\"\u003eCold-Chain Integrity\u003c\/b\u003e Peptide ligands are highly sensitive to thermal degradation. We utilize a strictly monitored Cold-Chain Logistics protocol within the USA. Your reagent travels from a climate-controlled facility directly to your laboratory, preventing the molecular breakdown often seen in non-domestic or unmonitored shipments.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"19,2,0\"\u003e\u003cb data-path-to-node=\"19,2,0\" data-index-in-node=\"0\"\u003eSequence Integrity Verification\u003c\/b\u003e Many generic sources offer high purity but broken peptide chains. We verify Peptide Integrity via Mass Spectrometry to ensure the full 39-amino acid sequence is completely intact and capable of successfully binding to both target receptors.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2 data-path-to-node=\"21\"\u003eRegulatory \u0026amp; Compliance Statement (RUO)\u003c\/h2\u003e\n\u003cp data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003eRegulatory Classification \u0026amp; Usage Disclaimer:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"23\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,0,0\"\u003e\u003cb data-path-to-node=\"23,0,0\" data-index-in-node=\"0\"\u003eStrictly RUO:\u003c\/b\u003e This product is exclusively classified as a Research Use Only (RUO) reagent.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,1,0\"\u003e\u003cb data-path-to-node=\"23,1,0\" data-index-in-node=\"0\"\u003eChemical Reference Standard:\u003c\/b\u003e It is supplied solely for \u003ci data-path-to-node=\"23,1,0\" data-index-in-node=\"55\"\u003ein-vitro\u003c\/i\u003e testing, cellular assays, and laboratory calibration.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,2,0\"\u003e\u003cb data-path-to-node=\"23,2,0\" data-index-in-node=\"0\"\u003eNot a Drug:\u003c\/b\u003e This compound has not been evaluated by the FDA for safety or efficacy in humans.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,3,0\"\u003e\u003cb data-path-to-node=\"23,3,0\" data-index-in-node=\"0\"\u003eHandling Protocol:\u003c\/b\u003e This reagent is a potent biological modulator. Researchers must wear appropriate PPE (nitrile gloves, protective eyewear, lab coat) during reconstitution and handling.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,4,0\"\u003e\u003cb data-path-to-node=\"23,4,0\" data-index-in-node=\"0\"\u003eSafety Data:\u003c\/b\u003e Always refer to the CAS 2023788-19-2 Material Safety Data Sheet (MSDS) before use.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,5,0\"\u003e\u003cb data-path-to-node=\"23,5,0\" data-index-in-node=\"0\"\u003eStrict Prohibition:\u003c\/b\u003e \u003cb data-path-to-node=\"23,5,0\" data-index-in-node=\"20\"\u003eAny intent to use this product for bodily introduction (injection or ingestion) in humans or animals is a direct violation of federal compliance protocols.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"25\"\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003eQ1: Is this product intended for human use?\u003c\/b\u003e \u003cb data-path-to-node=\"26\" data-index-in-node=\"44\"\u003eA: NO.\u003c\/b\u003e This is strictly a Chemical Reference Material for laboratory research. It is not a sterile pharmaceutical product and is not approved for human consumption, therapeutic application, or clinical diagnostics.\u003c\/p\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003eQ2: What does \"75 Format\" mean?\u003c\/b\u003e \u003cb data-path-to-node=\"27\" data-index-in-node=\"32\"\u003eA:\u003c\/b\u003e This refers to the total mass of the active lyophilized powder inside the container. It is specifically designed for preparing large-volume master stock solutions for multiple assays or longitudinal experiments.\u003c\/p\u003e\n\u003cp data-path-to-node=\"28\"\u003e\u003cb data-path-to-node=\"28\" data-index-in-node=\"0\"\u003eQ3: How do I dissolve the lyophilized cake?\u003c\/b\u003e \u003cb data-path-to-node=\"28\" data-index-in-node=\"44\"\u003eA:\u003c\/b\u003e The reagent is soluble in BAC Water or an appropriate sterile buffer solution. Researchers must calculate the molarity required for their specific assay before adding the solvent to ensure accurate concentrations.\u003c\/p\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eQ4: Can I freeze the solution after mixing?\u003c\/b\u003e \u003cb data-path-to-node=\"29\" data-index-in-node=\"44\"\u003eA:\u003c\/b\u003e Yes. Once reconstituted, we strongly recommend aliquoting the master solution into smaller, single-use units and storing them at -80°C. This prevents repeated freeze-thaw cycles, which will rapidly degrade the peptide sequence.\u003c\/p\u003e\n\u003cp data-path-to-node=\"30\"\u003e\u003cb data-path-to-node=\"30\" data-index-in-node=\"0\"\u003eQ5: Does this ligand display cross-reactivity with Tyrosine Kinase vectors?\u003c\/b\u003e \u003cb data-path-to-node=\"30\" data-index-in-node=\"76\"\u003eA:\u003c\/b\u003e It maintains a High Selectivity Profile. Structural binding assays confirm that Tirz is highly selective for G-Protein Coupled Receptors (GPCRs). It displays negligible binding affinity for the Tyrosine Kinase family, empowering researchers to isolate incretin signaling pathways without interference from divergent metabolic cascades.\u003c\/p\u003e\n\u003cp data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"0\"\u003eQ6: Why is the powder quantity visually small?\u003c\/b\u003e \u003cb data-path-to-node=\"31\" data-index-in-node=\"47\"\u003eA:\u003c\/b\u003e The lyophilization (freeze-drying) process removes all moisture, leaving a highly dense \"cake\" at the base of the vial. While the visual volume may appear small, the actual Mass Content is gravimetrically guaranteed.\u003c\/p\u003e\n\u003cp data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eQ7: Does this ligand interact with Nuclear Receptors?\u003c\/b\u003e \u003cb data-path-to-node=\"32\" data-index-in-node=\"54\"\u003eA:\u003c\/b\u003e No. This is a Peptide-Based Agonist. It strictly targets extracellular G-Protein Coupled Receptors (GPCRs) and does not share chemical properties with cholesterol-derived scaffolds or intracellular nuclear signaling agents.\u003c\/p\u003e\n\u003cp data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eQ8: What is the shelf life?\u003c\/b\u003e \u003cb data-path-to-node=\"33\" data-index-in-node=\"28\"\u003eA:\u003c\/b\u003e In its lyophilized (powder) state, it is stable for up to 24 months if stored desiccated at -20°C. Once dissolved in a solvent, it should be utilized immediately in your assay or frozen in aliquots at -80°C.\u003c\/p\u003e\n\u003cp data-path-to-node=\"34\"\u003e\u003cb data-path-to-node=\"34\" data-index-in-node=\"0\"\u003eQ9: Do you provide a Certificate of Analysis (COA)?\u003c\/b\u003e \u003cb data-path-to-node=\"34\" data-index-in-node=\"52\"\u003eA:\u003c\/b\u003e Yes. Every batch includes a COA verifying ≥99% purity and identity confirmation via both RP-HPLC and Mass Spectrometry.\u003c\/p\u003e\n\u003cp data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eQ10: Can this be used for \"Biohacking\"?\u003c\/b\u003e \u003cb data-path-to-node=\"35\" data-index-in-node=\"40\"\u003eA: Absolutely Not.\u003c\/b\u003e Any reference to personal use, biohacking, or lifestyle improvement blatantly violates our Terms of Service and will result in the immediate cancellation of the order and a permanent ban from our supply network.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!----\u003e\n\u003c\/div\u003e","brand":"BioLink Analytica","offers":[{"title":"10mg","offer_id":44907363663941,"sku":"TR10","price":99.0,"currency_code":"USD","in_stock":true},{"title":"20mg","offer_id":44907363729477,"sku":"TR20","price":129.0,"currency_code":"USD","in_stock":true},{"title":"30mg","offer_id":44907363762245,"sku":"TR30","price":149.0,"currency_code":"USD","in_stock":true},{"title":"50mg","offer_id":44907363795013,"sku":"TR50","price":179.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0729\/0060\/8069\/files\/TIRZ_-_TR10.png?v=1782365655"},{"product_id":"other-example-product-3","title":"RETATRUTIDE","description":"\u003ch2 data-path-to-node=\"2\"\u003eRetatrutide (RUO) | Triple GIP\/GLP-1\/Glucagon Agonist\u003c\/h2\u003e\n\u003cp data-path-to-node=\"3\"\u003eRetatrutide is a premier 39-amino acid unimolecular peptide engineered for potent triple-agonist activity. By simultaneously targeting the Gastric Inhibitory Polypeptide (GIP), Glucagon-Like Peptide-1 (GLP-1), and Glucagon (GCG) receptors, this compound offers a multifaceted approach to metabolic signaling research.\u003c\/p\u003e\n\u003cp data-path-to-node=\"4\"\u003eIts unique structure features a C20 fatty diacid moiety that facilitates high-affinity albumin binding. This critical modification protects the peptide from enzymatic degradation and extends its biological half-life to approximately 6 days, making it an ideal candidate for longitudinal studies in obesity, Type 2 Diabetes (T2D), and hepatic steatosis research models.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"5\"\u003eProduct Specifications\u003c\/h3\u003e\n\u003ctable data-path-to-node=\"6\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eProperty\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eDetail\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,1,0,0\"\u003e\u003cb data-path-to-node=\"6,1,0,0\" data-index-in-node=\"0\"\u003eProduct Name\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,1,1,0\"\u003eRetatrutide (Research Grade)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,2,0,0\"\u003e\u003cb data-path-to-node=\"6,2,0,0\" data-index-in-node=\"0\"\u003eCommon Name\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,2,1,0\"\u003eLY3437943\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,3,0,0\"\u003e\u003cb data-path-to-node=\"6,3,0,0\" data-index-in-node=\"0\"\u003eCAS Number\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,3,1,0\"\u003e2381089-83-2\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,4,0,0\"\u003e\u003cb data-path-to-node=\"6,4,0,0\" data-index-in-node=\"0\"\u003eMolecular Formula\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,4,1,0\"\u003e\u003cspan class=\"math-inline\" data-math=\"\\text{C}_{221}\\text{H}_{342}\\text{N}_{46}\\text{O}_{68}\" data-index-in-node=\"0\"\u003e$\\text{C}_{221}\\text{H}_{342}\\text{N}_{46}\\text{O}_{68}$\u003c\/span\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,5,0,0\"\u003e\u003cb data-path-to-node=\"6,5,0,0\" data-index-in-node=\"0\"\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,5,1,0\"\u003e4731 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,6,0,0\"\u003e\u003cb data-path-to-node=\"6,6,0,0\" data-index-in-node=\"0\"\u003eTarget Receptors\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,6,1,0\"\u003eGIP \/ GLP-1 \/ Glucagon (GCG)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,7,0,0\"\u003e\u003cb data-path-to-node=\"6,7,0,0\" data-index-in-node=\"0\"\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,7,1,0\"\u003e≥99% (HPLC Verified)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,8,0,0\"\u003e\u003cb data-path-to-node=\"6,8,0,0\" data-index-in-node=\"0\"\u003eEndotoxin Level\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,8,1,0\"\u003e\u0026lt;1.0 EU\/mg (Suitable for high-sensitivity assays)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,9,0,0\"\u003e\u003cb data-path-to-node=\"6,9,0,0\" data-index-in-node=\"0\"\u003eForm\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,9,1,0\"\u003eLyophilized White Powder\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,10,0,0\"\u003e\u003cb data-path-to-node=\"6,10,0,0\" data-index-in-node=\"0\"\u003eSolubility\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"6,10,1,0\"\u003eSoluble in sterile or bacteriostatic water\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3 data-path-to-node=\"8\"\u003eChemical Identity \u0026amp; Structural Mechanism\u003c\/h3\u003e\n\u003cp data-path-to-node=\"9\"\u003eRetatrutide integrates activity at the Glucagon Receptor (GCGR) alongside GIP and GLP-1 to create a \"Triple Synergy\" mechanism that fundamentally alters the energy balance equation.\u003c\/p\u003e\n\u003cul data-path-to-node=\"10\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,0,0\"\u003e\u003cb data-path-to-node=\"10,0,0\" data-index-in-node=\"0\"\u003eStructure-Activity Relationship (SAR):\u003c\/b\u003e The peptide backbone is derived from GIP but explicitly modified to introduce targeted Glucagon activity. The attached C20 fatty acid moiety is the primary driver of its extended 6-day half-life, allowing for sustained metabolic observation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,1,0\"\u003e\u003cb data-path-to-node=\"10,1,0\" data-index-in-node=\"0\"\u003eTuned Potency:\u003c\/b\u003e The molecule is engineered with a highly specific hierarchy of receptor potency: maximum affinity at GIP for lipid buffering, moderate affinity at GLP-1 for satiety induction, and carefully tuned affinity at Glucagon to drive thermogenesis and energy expenditure without inducing hyperglycemia.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"12\"\u003eWhy Leading Labs Source Retatrutide from Profound Aminos\u003c\/h3\u003e\n\u003cp data-path-to-node=\"13\"\u003eSuccessful research demands absolute consistency. Retatrutide is a complex, acylated peptide that degrades rapidly if mishandled. We safeguard your data integrity through rigorous operational standards.\u003c\/p\u003e\n\u003cul data-path-to-node=\"14\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-path-to-node=\"14,0,0\" data-index-in-node=\"0\"\u003eLot-Specific Transparency:\u003c\/b\u003e We eliminate the \"black box\" of reagent sourcing. Every vial includes a Certificate of Analysis (COA) explicitly confirming the presence of the critical C20 fatty acid side chain, alongside HPLC analysis verifying ≥99% purity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-path-to-node=\"14,1,0\" data-index-in-node=\"0\"\u003eUSA-Based Cold-Chain Logistics:\u003c\/b\u003e Thermal stress causes hydrolysis of the acylated side chain. Our stock is strictly maintained at -20°C in our US-based facility. By shipping directly to your lab, we minimize thermal exposure so you receive a research-ready molecule, not a degraded byproduct.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,2,0\"\u003e\u003cb data-path-to-node=\"14,2,0\" data-index-in-node=\"0\"\u003eThe \"Triple G\" Advantage:\u003c\/b\u003e Unlike dual agonists, sourcing true triple-agonist Retatrutide unlocks the ability to study energy expenditure and massive hepatic defatting simultaneously, offering the highest Return on Investigation (ROI) in current metabolic modeling.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"16\"\u003eRetatrutide vs. Competitors\u003c\/h3\u003e\n\u003ctable data-path-to-node=\"17\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eParameter\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eRetatrutide (Triple)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eTirzepatide (Dual)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eSemaglutide (Mono)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,0,0\"\u003e\u003cb data-path-to-node=\"17,1,0,0\" data-index-in-node=\"0\"\u003eMechanism\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,1,0\"\u003eGIP \/ GLP-1 \/ Glucagon\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,2,0\"\u003eGIP \/ GLP-1\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,3,0\"\u003eGLP-1\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,0,0\"\u003e\u003cb data-path-to-node=\"17,2,0,0\" data-index-in-node=\"0\"\u003eMetabolic Focus\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,1,0\"\u003eAppetite Suppression + Caloric Burn\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,2,0\"\u003eAppetite Suppression\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,3,0\"\u003eAppetite Suppression\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,0,0\"\u003e\u003cb data-path-to-node=\"17,3,0,0\" data-index-in-node=\"0\"\u003eWeight Loss (High Dose)\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,1,0\"\u003e~24% – 29%\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,2,0\"\u003e~21%\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,3,0\"\u003e~15%\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,0,0\"\u003e\u003cb data-path-to-node=\"17,4,0,0\" data-index-in-node=\"0\"\u003eLiver Fat Reduction\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,1,0\"\u003e\u0026gt;86% (Defatting)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,2,0\"\u003eModerate\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,3,0\"\u003eLow\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3 data-path-to-node=\"19\"\u003eResearch Context \u0026amp; Clinical Insights (2025–2026)\u003c\/h3\u003e\n\u003cul data-path-to-node=\"20\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,0,0\"\u003e\u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"0\"\u003eObesity \u0026amp; Osteoarthritis (TRIUMPH-4):\u003c\/b\u003e Phase 3 trials released in December 2025 demonstrated a mean weight reduction of 28.7% at the 12 mg dose. Crucially, the cohort saw a 75.8% reduction in knee pain scores, indicating benefits extend well beyond weight loss into structural and inflammatory improvements.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,1,0\"\u003e\u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"0\"\u003eType 2 Diabetes (TRANSCEND-T2D-1):\u003c\/b\u003e Currently investigated under NCT06354660, this pivotal trial evaluates Retatrutide against a placebo in adults with inadequate glycemic control, aiming to replicate the unparalleled weight reductions observed in non-diabetic cohorts.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,2,0\"\u003e\u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"0\"\u003eHepatic Health (MASLD):\u003c\/b\u003e In Phase 2 substudies, \u0026gt;90% of subjects with metabolic dysfunction-associated steatotic liver disease (MASLD) achieved normal liver fat levels (\u0026lt;5%), positioning this molecule as a leading candidate for reversing hepatic steatosis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"22\"\u003eRegulatory \u0026amp; Compliance Status\u003c\/h3\u003e\n\u003cul data-path-to-node=\"23\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,0,0\"\u003e\u003cb data-path-to-node=\"23,0,0\" data-index-in-node=\"0\"\u003eFDA Status:\u003c\/b\u003e Investigational New Drug (IND) currently in Phase 3 clinical trials. Not FDA-approved.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,1,0\"\u003e\u003cb data-path-to-node=\"23,1,0\" data-index-in-node=\"0\"\u003eWADA Status:\u003c\/b\u003e Prohibited under S2 (Peptide Hormones).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"23,2,0\"\u003e\u003cb data-path-to-node=\"23,2,0\" data-index-in-node=\"0\"\u003eUsage:\u003c\/b\u003e Strictly for Laboratory Research Use Only (RUO).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"25\"\u003eFrequently Asked Questions\u003c\/h3\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003eWhy is Retatrutide considered the “Gold Standard” over Tirzepatide and Semaglutide for obesity research?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"26\"\u003eRetatrutide represents a paradigm shift from traditional treatment to \"medical bariatrics.\" While Semaglutide peaks at ~15% weight loss and Tirzepatide at ~21%, Retatrutide has demonstrated a staggering 28.7% mean body weight reduction in Phase 3 trials. It offers the highest therapeutic ceiling currently available in pharmacotherapy.\u003c\/p\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003eDoes Retatrutide offer distinct advantages for Type 2 Diabetes (T2D) modeling?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"27\"\u003eAbsolutely. In T2D trials, it achieved the largest weight reduction ever reported in a diabetic population (~17% vs. the typical 13%), alongside HbA1c reductions of up to 2.0%. It is a superior candidate for studying the reversal of \"diabesity\" and restoring normoglycemia.\u003c\/p\u003e\n\u003cp data-path-to-node=\"28\"\u003e\u003cb data-path-to-node=\"28\" data-index-in-node=\"0\"\u003eHow does the \"Triple Agonist\" mechanism drive superior results?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"28\"\u003eThe addition of the Glucagon (GCG) receptor is the blockbuster differentiator. While older GLP-1\/GIP agonists strictly suppress energy intake, Retatrutide attacks obesity on two fronts: it lowers caloric intake while actively increasing energy expenditure (thermogenesis) via glucagon signaling, helping bypass traditional metabolic adaptation plateaus.\u003c\/p\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eWith potent Glucagon activity, is there a risk of hyperglycemia in research subjects?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"29\"\u003eThis is a common misconception. Retatrutide utilizes a perfectly \"tuned\" potency ratio where the robust insulinotropic effects of GIP and GLP-1 fully counterbalance the glucagon component. Clinical data confirms improved glycemic control despite glucagon activation.\u003c\/p\u003e\n\u003cp data-path-to-node=\"30\"\u003e\u003cb data-path-to-node=\"30\" data-index-in-node=\"0\"\u003eIs the molecule stable enough for long-duration preclinical trials?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"30\"\u003eYes. The engineered C20 fatty diacid moiety promotes albumin binding, extending the half-life to approximately 6 days. This supports convenient weekly administration protocols, reducing variable stress on research subjects.\u003c\/p\u003e\n\u003cblockquote data-path-to-node=\"32\"\u003e\n\u003cp data-path-to-node=\"32,0\"\u003e\u003cb data-path-to-node=\"32,0\" data-index-in-node=\"0\"\u003eLABORATORY DISCLAIMER\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"32,0\"\u003eProducts sold by Profound Aminos are strictly for scientific research, in vitro testing, and laboratory experimentation. These products are not intended to be used as foods, drugs, or cosmetics. The introduction of these products into humans or animals is strictly prohibited. They must not be misbranded, misused, mislabeled, or used for any purpose other than authorized scientific investigation.\u003c\/p\u003e\n\u003cp data-path-to-node=\"32,1\"\u003eAll products are sold as a lyophilized (freeze-dried) powder in sealed sterile vials and require reconstitution and standard laboratory equipment for proper handling. While packaging and labeling are matched closely to our website representations, minor deviations may occur.\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp data-path-to-node=\"34\"\u003eWould you like me to tailor this enhanced copy further for a specific medium, such as a website product page, an email marketing campaign, or a downloadable technical data sheet?\u003c\/p\u003e","brand":"BioLink Analytica","offers":[{"title":"10mg","offer_id":44904780398661,"sku":"RT10","price":99.0,"currency_code":"USD","in_stock":true},{"title":"20mg","offer_id":44904780464197,"sku":"RT20","price":159.0,"currency_code":"USD","in_stock":true},{"title":"30mg","offer_id":44904780496965,"sku":"RT30","price":199.0,"currency_code":"USD","in_stock":true},{"title":"50mg","offer_id":44904780529733,"sku":"RT50","price":284.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0729\/0060\/8069\/files\/RETATRUTIDE_-_10_MG.png?v=1782365654"},{"product_id":"other-example-product-4","title":"GHK-CU","description":"\u003ch1 data-path-to-node=\"2\"\u003eGHK-Cu (Copper Tripeptide-1) Analytical Reagent\u003c\/h1\u003e\n\u003cp data-path-to-node=\"3\"\u003e\u003cb data-path-to-node=\"3\" data-index-in-node=\"0\"\u003eGHK-Cu\u003c\/b\u003e is a high-purity, naturally occurring copper-complexed tripeptide, provided as a stable lyophilized powder strictly for \u003ci data-path-to-node=\"3\" data-index-in-node=\"127\"\u003ein vitro\u003c\/i\u003e laboratory investigation. Structurally defined as Glycyl-L-Histidyl-L-Lysine complexed with Cu²⁺, this compound is extensively documented in peer-reviewed literature for its pivotal roles in extracellular matrix (ECM) regulation, copper coordination chemistry, and diverse cellular signaling pathways.\u003c\/p\u003e\n\u003cul data-path-to-node=\"4\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,0,0\"\u003e\u003cb data-path-to-node=\"4,0,0\" data-index-in-node=\"0\"\u003eQuantity:\u003c\/b\u003e Supplied at 50 analytical mass units.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,1,0\"\u003e\u003cb data-path-to-node=\"4,1,0\" data-index-in-node=\"0\"\u003eQuality Control:\u003c\/b\u003e Uncompromising quality guaranteed, with ≥99% purity verified by RP-HPLC and molecular identity confirmed via LC-MS.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,2,0\"\u003e\u003cb data-path-to-node=\"4,2,0\" data-index-in-node=\"0\"\u003eRegulatory Warning:\u003c\/b\u003e This product is an analytical research reagent. It is strictly prohibited for human or animal consumption, parenteral administration, or any application outside a controlled laboratory setting.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"6\"\u003eTechnical Specifications\u003c\/h2\u003e\n\u003cul data-path-to-node=\"7\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,0,0\"\u003e\u003cb data-path-to-node=\"7,0,0\" data-index-in-node=\"0\"\u003eChemical Class:\u003c\/b\u003e Copper-Complexed Tripeptide Reagent\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,1,0\"\u003e\u003cb data-path-to-node=\"7,1,0\" data-index-in-node=\"0\"\u003eINCI Name:\u003c\/b\u003e Copper Tripeptide-1\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,2,0\"\u003e\u003cb data-path-to-node=\"7,2,0\" data-index-in-node=\"0\"\u003ePhysical Format:\u003c\/b\u003e Lyophilized Powder, Hermetically Sealed Sterile Container\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,3,0\"\u003e\u003cb data-path-to-node=\"7,3,0\" data-index-in-node=\"0\"\u003eNet Reagent Content:\u003c\/b\u003e 50 analytical mass units per sealed container\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,4,0\"\u003e\u003cb data-path-to-node=\"7,4,0\" data-index-in-node=\"0\"\u003eCAS Registry:\u003c\/b\u003e 89030-95-5\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,5,0\"\u003e\u003cb data-path-to-node=\"7,5,0\" data-index-in-node=\"0\"\u003ePubChem CID:\u003c\/b\u003e 378611\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,6,0\"\u003e\u003cb data-path-to-node=\"7,6,0\" data-index-in-node=\"0\"\u003eMolecular Formula:\u003c\/b\u003e C₁₄H₂₃CuN₆O₄\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,7,0\"\u003e\u003cb data-path-to-node=\"7,7,0\" data-index-in-node=\"0\"\u003eMolecular Weight:\u003c\/b\u003e 340.4 Da (peptide backbone) + Cu²⁺ coordination\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,8,0\"\u003e\u003cb data-path-to-node=\"7,8,0\" data-index-in-node=\"0\"\u003eAnalytical Purity:\u003c\/b\u003e ≥99% by RP-HPLC\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,9,0\"\u003e\u003cb data-path-to-node=\"7,9,0\" data-index-in-node=\"0\"\u003eIdentity Confirmation:\u003c\/b\u003e LC-MS (Molecular weight and sequence verified)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,10,0\"\u003e\u003cb data-path-to-node=\"7,10,0\" data-index-in-node=\"0\"\u003eEndotoxin Screening:\u003c\/b\u003e \u0026lt;0.25 EU (LAL assay)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,11,0\"\u003e\u003cb data-path-to-node=\"7,11,0\" data-index-in-node=\"0\"\u003eCopper Stoichiometry:\u003c\/b\u003e Cu:peptide ratio verified by ICP or colorimetric method\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,12,0\"\u003e\u003cb data-path-to-node=\"7,12,0\" data-index-in-node=\"0\"\u003eReconstitution Buffer:\u003c\/b\u003e Aqueous laboratory buffer (pH 4–6 recommended for complex stability)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,13,0\"\u003e\u003cb data-path-to-node=\"7,13,0\" data-index-in-node=\"0\"\u003eStorage (Lyophilized):\u003c\/b\u003e 2–8°C, desiccated, light-protected\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,14,0\"\u003e\u003cb data-path-to-node=\"7,14,0\" data-index-in-node=\"0\"\u003eStorage (In Solution):\u003c\/b\u003e −20°C, single-use aliquots advised\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,15,0\"\u003e\u003cb data-path-to-node=\"7,15,0\" data-index-in-node=\"0\"\u003eRegulatory Class:\u003c\/b\u003e Research Use Only (RUO)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"9\"\u003eCopper Coordination Chemistry \u0026amp; Research Mechanisms\u003c\/h2\u003e\n\u003cp data-path-to-node=\"10\"\u003eUnlike single-mechanism research tools, GHK-Cu operates across multiple documented signaling pathways simultaneously, making it uniquely valuable for investigating the intersection of copper coordination chemistry, ECM remodeling, and inflammatory pathway modulation.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"11\"\u003eCoordination Chemistry Profile\u003c\/h3\u003e\n\u003cul data-path-to-node=\"12\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,0,0\"\u003e\u003cb data-path-to-node=\"12,0,0\" data-index-in-node=\"0\"\u003eCu²⁺ Coordination Sites:\u003c\/b\u003e Imidazole N (His) + alpha-amino N (Gly) + deprotonated amide N\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,1,0\"\u003e\u003cb data-path-to-node=\"12,1,0\" data-index-in-node=\"0\"\u003eLog Stability Constant:\u003c\/b\u003e ~16.44 (PMC3359723)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,2,0\"\u003e\u003cb data-path-to-node=\"12,2,0\" data-index-in-node=\"0\"\u003eConditional Kd at pH 7.4:\u003c\/b\u003e Picomolar range (PMC7503498)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,3,0\"\u003e\u003cb data-path-to-node=\"12,3,0\" data-index-in-node=\"0\"\u003eComplex Stability:\u003c\/b\u003e Most stable between pH 4–6; dissociation occurs at extreme pH levels.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,4,0\"\u003e\u003cb data-path-to-node=\"12,4,0\" data-index-in-node=\"0\"\u003eRedox Chemistry:\u003c\/b\u003e Cu(II)GHK is reduced by glutathione via thiolate intermediates (PMC8653159).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"13\"\u003e2026 Laboratory Applications\u003c\/h3\u003e\n\u003col start=\"1\" data-path-to-node=\"14\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-path-to-node=\"14,0,0\" data-index-in-node=\"0\"\u003eECM Remodeling \u0026amp; Collagen Synthesis:\u003c\/b\u003e Investigated for the stimulation of collagen synthesis in fibroblast cultures at pico-to-nanomolar concentrations, and differential regulation of small proteoglycans (decorin upregulated; biglycan downregulated).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-path-to-node=\"14,1,0\" data-index-in-node=\"0\"\u003eMMP\/TIMP Protease Balance:\u003c\/b\u003e Used to study the modulation of metalloproteinases and inhibitors, consistent with a tissue-remodeling phenotype.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,2,0\"\u003e\u003cb data-path-to-node=\"14,2,0\" data-index-in-node=\"0\"\u003eAnti-Inflammatory Pathway Modulation:\u003c\/b\u003e Applied in research extending to SIRT1 activation, p-STAT3 downregulation, improvement of mucosal barrier proteins (ZO-1, occludin), and reduction of Th17-driven inflammatory signaling.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,3,0\"\u003e\u003cb data-path-to-node=\"14,3,0\" data-index-in-node=\"0\"\u003eBiomaterials \u0026amp; Delivery Systems:\u003c\/b\u003e Utilized in the development of advanced delivery systems, including dimeric copper-peptide hydrogels and pH-responsive biomaterials.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2 data-path-to-node=\"16\"\u003eComparative Research Context\u003c\/h2\u003e\n\u003ctable data-path-to-node=\"17\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFeature\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eGHK-Cu\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eMatrixyl (Pal-KTTKS)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eLL-37\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eGHK (Apo-peptide)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,0,0\"\u003e\u003cb data-path-to-node=\"17,1,0,0\" data-index-in-node=\"0\"\u003eChemical Class\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,1,0\"\u003eCu²⁺-complexed tripeptide\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,2,0\"\u003eα-amino fatty acid pentapeptide\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,3,0\"\u003eHost-defense cathelicidin\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,1,4,0\"\u003eApo-tripeptide (no copper)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,0,0\"\u003e\u003cb data-path-to-node=\"17,2,0,0\" data-index-in-node=\"0\"\u003ePrimary Research Focus\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,1,0\"\u003eECM + copper coordination + NF-κB\/SIRT1\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,2,0\"\u003eCollagen synthesis only\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,3,0\"\u003eAntimicrobial + immune\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,2,4,0\"\u003eECM (without copper activity)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,0,0\"\u003e\u003cb data-path-to-node=\"17,3,0,0\" data-index-in-node=\"0\"\u003eCopper Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,1,0\"\u003eCu²⁺ coordination verified\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,2,0\"\u003eNone\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,3,0\"\u003eNone\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,3,4,0\"\u003eAbsent\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,0,0\"\u003e\u003cb data-path-to-node=\"17,4,0,0\" data-index-in-node=\"0\"\u003eCytokine Regulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,1,0\"\u003eNF-κB, MAPK, SIRT1\/STAT3\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,2,0\"\u003eLimited\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,3,0\"\u003eLimited\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,4,4,0\"\u003eLimited\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,5,0,0\"\u003e\u003cb data-path-to-node=\"17,5,0,0\" data-index-in-node=\"0\"\u003eUS Search Volume\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,5,1,0\"\u003e90,500\/month (+1,016% YoY)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,5,2,0\"\u003eLower\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,5,3,0\"\u003eLower\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,5,4,0\"\u003eLower\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,6,0,0\"\u003e\u003cb data-path-to-node=\"17,6,0,0\" data-index-in-node=\"0\"\u003eCOA Requirement\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,6,1,0\"\u003eCu stoichiometry + HPLC + MS\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,6,2,0\"\u003eHPLC only\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,6,3,0\"\u003eHPLC + MS\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,6,4,0\"\u003eHPLC + MS\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,7,0,0\"\u003e\u003cb data-path-to-node=\"17,7,0,0\" data-index-in-node=\"0\"\u003eRegulatory Class\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,7,1,0\"\u003eRUO\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,7,2,0\"\u003eRUO\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,7,3,0\"\u003eRUO\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"17,7,4,0\"\u003eRUO\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2 data-path-to-node=\"19\"\u003eWhy Source From BioLink Analytica?\u003c\/h2\u003e\n\u003cp data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003e1. Copper Stoichiometry Verification – Beyond Basic Purity\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"20\"\u003eStandard HPLC purity confirms peptide content but cannot confirm whether copper coordination is complete, partial, or absent. Our GHK-Cu batches include verification of the Cu:peptide stoichiometric ratio, ensuring researchers receive the complexed form (Cu(II)GHK) required for copper-mediated pathway research, rather than just the apo-peptide (GHK).\u003c\/p\u003e\n\u003cp data-path-to-node=\"21\"\u003e\u003cb data-path-to-node=\"21\" data-index-in-node=\"0\"\u003e2. pH-Stable Formulation Intelligence\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"21\"\u003ePublished physicochemical characterization documents GHK-Cu complex stability as highly pH-dependent, with optimal stability at pH 4–6. Our technical data sheet includes precise storage and reconstitution buffer guidance aligned with published stability data, protecting your assay integrity from formulation-induced artifacts.\u003c\/p\u003e\n\u003cp data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003e3. Cold-Chain Integrity \u0026amp; Domestic Dispatch\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"22\"\u003eCopper-peptide complexes are highly sensitive to thermal and oxidative degradation. BioLink Analytica ships exclusively within the USA via monitored cold-chain logistics from a climate-controlled facility, completely eliminating the uncontrolled temperature excursions often documented in international shipments.\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"24\"\u003eRegulatory \u0026amp; Compliance Statement\u003c\/h2\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY (RUO). NOT FOR HUMAN OR ANIMAL APPLICATION.\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eRegulatory Status:\u003c\/b\u003e Research Use Only (RUO) under the U.S. Federal Framework.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eFDA Status:\u003c\/b\u003e No FDA-approved GHK-Cu drug product exists. It holds cosmetic ingredient status only for finished products (INCI: Copper Tripeptide-1).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,2,0\"\u003e\u003cb data-path-to-node=\"26,2,0\" data-index-in-node=\"0\"\u003eNot a Drug\/Supplement:\u003c\/b\u003e Not evaluated by the FDA for safety or efficacy in any clinical application. Not a dietary supplement, nutraceutical, or consumer product.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,3,0\"\u003e\u003cb data-path-to-node=\"26,3,0\" data-index-in-node=\"0\"\u003ePPE Required:\u003c\/b\u003e Gloves, lab coat, and protective eyewear are mandatory. Copper is biologically active; handle strictly as a bioactive chemical reagent.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,4,0\"\u003e\u003cb data-path-to-node=\"26,4,0\" data-index-in-node=\"0\"\u003eStrict Prohibition:\u003c\/b\u003e Promoting, distributing, or using this research reagent for any application involving administration to living organisms is strictly prohibited under U.S. federal law.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003ci data-path-to-node=\"27\" data-index-in-node=\"0\"\u003eDisclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/i\u003e\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"29\"\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp data-path-to-node=\"30\"\u003e\u003cb data-path-to-node=\"30\" data-index-in-node=\"0\"\u003eQ1: Is GHK-Cu intended for consumption or administration?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"30\"\u003e\u003cb data-path-to-node=\"30\" data-index-in-node=\"58\"\u003eA:\u003c\/b\u003e No. GHK-Cu is strictly classified as a Research Use Only (RUO) laboratory reagent. It is not approved, labeled, or intended for consumption, parenteral administration, therapeutic use, or any diagnostic application. Purchase confirms your agreement to institutional laboratory research use only.\u003c\/p\u003e\n\u003cp data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"0\"\u003eQ2: What is the difference between GHK (apo-peptide) and GHK-Cu?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"65\"\u003eA:\u003c\/b\u003e GHK is the apo-tripeptide (glycyl-L-histidyl-L-lysine) \u003ci data-path-to-node=\"31\" data-index-in-node=\"123\"\u003ewithout\u003c\/i\u003e copper coordination. GHK-Cu is the copper-complexed form where Cu²⁺ is coordinated by the imidazole nitrogen of histidine, the alpha-amino group of glycine, and the deprotonated amide nitrogen. Researchers requiring copper-mediated pathway investigation must use the complexed GHK-Cu form to ensure proper redox reactivity.\u003c\/p\u003e\n\u003cp data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eQ3: What analytical data is provided with each batch?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"54\"\u003eA:\u003c\/b\u003e Each batch includes: (1) RP-HPLC purity ≥99%, (2) LC-MS molecular weight confirmation, (3) Cu:peptide stoichiometric ratio verification, (4) endotoxin screening \u0026lt;0.25 EU, (5) lot number for full traceability, and (6) storage and stability conditions. A comprehensive Certificate of Analysis (COA) is available per batch.\u003c\/p\u003e\n\u003cp data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eQ4: What is the recommended reconstitution buffer for laboratory use?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"70\"\u003eA:\u003c\/b\u003e GHK-Cu complex stability is optimally maintained at pH 4–6. For most \u003ci data-path-to-node=\"33\" data-index-in-node=\"142\"\u003ein-vitro\u003c\/i\u003e assays, an aqueous buffer at pH 5–6 is recommended. Researchers must verify pH compatibility with their specific cell culture medium and assay conditions, and design experiments with appropriate redox controls.\u003c\/p\u003e\n\u003cp data-path-to-node=\"34\"\u003e\u003cb data-path-to-node=\"34\" data-index-in-node=\"0\"\u003eQ5: What is the FDA regulatory status of GHK-Cu?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"34\"\u003e\u003cb data-path-to-node=\"34\" data-index-in-node=\"49\"\u003eA:\u003c\/b\u003e In the US, it has three distinct contexts: (1) As a cosmetic ingredient (INCI: copper tripeptide-1) in finished products. (2) As a research chemical, compliant with laboratory safety frameworks (OSHA). (3) As a compounded substance under Section 503A\/503B oversight. \u003cb data-path-to-node=\"34\" data-index-in-node=\"319\"\u003eNo FDA-approved GHK-Cu drug product exists.\u003c\/b\u003e This product is supplied exclusively as an RUO reagent.\u003c\/p\u003e\n\u003cp data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eQ6: Is GHK-Cu the same as Matrixyl or other cosmetic research peptides?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"72\"\u003eA:\u003c\/b\u003e No. Matrixyl (Pal-KTTKS) is a fatty acid-conjugated pentapeptide with a different amino acid sequence and no copper coordination activity. GHK-Cu is uniquely characterized by its Cu²⁺ chelation chemistry, making them chemically and mechanistically distinct compounds.\u003c\/p\u003e","brand":"BioLink Analytica","offers":[{"title":"50mg","offer_id":44904708636741,"sku":"GHK-CU-50","price":99.0,"currency_code":"USD","in_stock":true},{"title":"100mg","offer_id":44904708735045,"sku":"GHK-CU-100","price":190.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0729\/0060\/8069\/files\/GHKCU_-_CU50.png?v=1782365652"}],"url":"https:\/\/www.biolinkanalytica.com\/collections\/other-example-products.oembed","provider":"BioLink Analytica","version":"1.0","type":"link"}